Clinical Systematic Reviews for Health Tech

Summary

BoxHealth conducted a clinical systematic review of literature relating to the predictive accuracy of two vital signs (respiratory rate and oxygen saturation) for predicting worsening severity in COVID-19 patients.

Challenge

A HealthTech company had developed a diagnostic product for COVID-19 detection in patients in isolation. They wanted to evidence the correlation (if it existed) between the vital sign their product used and its predictive accuracy in determining COVID-19 hospitalisation. In addition, how accurate it was compared to other common vital sign measurements for COVID-19 diagnosis.

Solution

We ran a systematic review of the clinical research and synthesised the data from the available papers into a report for the company. Impartially summarising and describing the known research on this area, a total of 2889 articles were screened for relevant content, of which 60 full-text publications were included. This provided the company with an evidence base to work from in terms of showing how accurate their measurement system has been in studies from all over the world. The research also was formatted and submitted to an academic journal for the company to be able to point to a peer-reviewed publication, related to its technology.